David Pépin, PhD
Associate Professor, Surgery | Harvard Medical School, Boston, MA USA
Associate Director, Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA USA
Associate Molecular Biologist, Surgery | Simches Research Center, Massachusetts General Hospital, Boston, MA USA
Project: Single treatment with AAV9 anti-Müllerian hormone as an ideal permanent contraceptive
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Dr. Pépin joined the Harvard Medical School faculty in 2014 where he holds the title of Associate Professor in the Department of Surgery at the Massachusetts General Hospital.
Dr. Pépin was trained as a reproductive biologist at the University of Ottawa, Canada, where he completed a PhD studying the regulation of follicle development in the ovary. His current research interests include both female reproductive development and the development of therapeutics for women’s health. Dr. Pépin has investigated the role of the anti-Müllerian hormone (AMH) in female reproduction and particularly in the context of ovarian function and disease. His laboratory was the first to describe the contraceptive effect of superphysiological AMH in animal models and elucidate its mechanism of action at the single cell level. He is currently developing therapeutics in late preclinical stage for contraception, assisted reproduction, oncofertility, and reproductive aging. Importantly, he leads the research efforts to develop a non-surgical permanent contraceptive for use in companion animals (cats and dogs) based on viral gene therapy delivery of AMH.